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Several lines of evidence indicate lifestyle-induced insulin malfunction, referred to as insulin resistance, as a decisive factor in many disease states. Researchers have for long assumed that overfatness/obesity causes insulin resistance, which in turn causes type 2 diabetes (virtually all obese and diabetic individuals have marked insulin resistance). More recent evidence has however demonstrated that insulin resistance may well be the cause of overfatness/obesity as well as type 2 diabetes and possibly other lifestyle-related diseases. For example, it has been demonstrated that appropriate exercise, more regular food intake and reducing glycemic load all can reverse insulin resistance in overfat individuals, which means that lifestyle rather than the fact of being fat promotes insulin resistance.
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